徐芳 教授
E-mail: fxu@sdu.edu.cn
个人简介
徐芳， 博士生导师，国家高层次青年人才，山东省“泰山学者特聘专家”，山东大学“杰出中青年学者”，山东省杰出青年基金获得者，山东大学“齐鲁青年学者”
教育背景
2009.01-2014.12 加拿大英属哥伦比亚大学(University of British Columbia, UBC), 植物学,博士
2004.09-2008.06 山东大学，国家生命科学与技术基地班，本科
工作经历
2019.05-至今 山东大学， 教授
2015.03-2019.05 美国冷泉港 (Cold Spring Harbor Laboratory，CSHL), 博士后
2008.07-2008.12 北京生命科学研究所， 科研助理
研究方向
1、玉米干细胞组织发育的遗传基础及调控机理研究.
2、植物发育与免疫平衡的分子机制研究；
3、基因编辑与作物精确分子育种等。
主持课题
2019-2023：国家海外高层次青年人才项目
2019-2024: 山东大学“齐鲁青年学者” 人才项目
2019-2024: 山东省“泰山学者青年学者” 项目，结题考核优秀
2025-2029：山东省“泰山学者特聘专家”项目
2021-2024: 国家自然科学基金青年项目
2025-2027：山东省杰出青年基金项目
2023-2026：国家自然科学基金地区联合重点项目子课题
2022-2027：国家重点研发计划子课题
代表性论文
1. Wang J, Zheng Q, Zhang R, Huang Z, Wu Q, Liu L, Ning Q*, Jackson D* and Xu F*. Heterozygous fasciated ear mutations improve yield traits in inbred and hybrid maize lines. Plant Physiology, 2024, In press. *Correspondence authors.
2. Yang RS#, Xu F#, Zhong WS, Wang YM, Dong L, Shi YN, Tang TJ, Sheng HJ, Jackson D*, Yang F*. Glutaredoxins regulate maize inflorescence meristem development via redox control of TGA transcriptional activity. Nature Plant, 2021, 7:1589-1601. #Equal contribution.
3. Nie S#, Wang B#, Ding H#…. Pan C, Huang H, Yuan G, Lan H, Nie Y, Li X, Zhao X, Zhang X, Pan G, Wu Q*, Xu F*, Zhang Z*. Genome assembly of the Chinese maize elite inbred line RP125 and its EMS mutant collection provide new resources for maize genetics research and crop improvement. The Plant Journal, 2021,108:40-54. *Correspondence authors.
4. Tian H, Wu Z, Chen S, Ao K, Huang W, Yaghmaiean H, Sun T, Xu F, Zhang Y, Wang S, Li X*, Zhang Y*. Activation of TIR signalling boosts pattern-triggered immunity. Nature, 2021, 598:500-503.
5. Xiao M, Wang J, Xu F*. Methylation hallmarks on the histone tail as a linker of osmotic stress and gene transcription. Frontiers in Plant Science. 2022, 13:967607.
6. Huang XX, Wang Y, Lin JS, Chen L, Li YJ, Liu Q, Wang GF, Xu F, Liu L, Hou BK*. The novel pathogen-responsive glycosyltransferase UGT73C7 mediates the redirection of phenylpropanoid metabolism and promotes SNC1-dependent Arabidopsis immunity. The Plant Journal, 2021, 107:149-165
7. Wu Q#, Xu F#, Liu L, Char SN, Ding Y, Je BI, Schmelz E, Yang B, Jackson D. The maize heterotrimeric G protein β subunit controls shoot meristem development and immune responses. PNAS, 2020, 117:1799-1805. #共同第一.
该文章被PNAS同期突出评论“Shoot meristem maintenance and immune response signaling converge at the G protein β subunit”
8. Xu F and Jackson D. Learning from CIK plants. Nature Plants, 2018, 4:195-196.
9. Je BI#, Xu F#, Wu Q, Liu L, Meeley R, Gallagher JP, Corcilius L, Payne RJ, Bartlett ME and Jackson D. The CLAVATA receptor FASCIATED EAR2 responds to distinct CLE peptides by signaling through two downstream effectors. Elife, 2018, eLife.35673. #共同第.一作者.
10. Wu Q#, Xu F# and Jackson D. All together now, a magical mystery tour of the maize shoot meristem. Current Opinion in Plant Biology, 2018, 45: 26-35. #共同第一作者.
11. Dong X#, Ao K#, Xu F#, Johnson K, Wu Y, Li L, Xia S, Liu Y, Huang Y, Rodriguez E, Chen X, Chen S, Zhang Y, Petersen M and Li X. Distinct E3 ligases regulate individual components of paired typical NLR immune receptors. Nature Plants, 2018, 4: 699-710. #共同第一作者.
12. Xu F#, Huang Y#, Li L#, Gannon P, Kapos P, Linster E, Bienvenut W, Polevoda B, Wirtz M, Meinnel T, Hell R, Giglione C, Chen S, Zhang Y and Li X. Two N-terminal acetyltransferases antagonistically control the stability of a Nod-like receptor in Arabidopsis. The Plant Cell, 2015, 27:1-17. #共同第一作者.
The above paper was highlighted in Nature Plant: Immunity: Antagonistic acetylases doi:10.1038/nplants.2015.84
13. Xu F, Kapos P, Li M, Zhang Y and Li X. NLR-associating transcription factor bHLH84 and its paralogs function redundantly in plant immunity. Plos Pathogens, 2014, e1004312.
14. Xu F#, Cheng YT#, Li M and Li X. P-loop-dependent NLR SNC1 can oligomerize and activate immunity in the nucleus. Molecular Plant, 2014, 7: 1801–1804. #共同第一作者.
15. Xu F, Xu S, Wiermer M, Zhang Y, Li X. (2012) The cyclin L homolog MOS12 and the MOS4-associated complex are required for the proper splicing of plant resistance genes. The Plant Journal. 70(6):916-28.
16. Xu F#, Zhu C#, Cevik V#, Johnson K, Liu Y, Sohn K, Holub E, Jones J, Liu Y, Li X. (2015). Autoimmunity conferred by chs3-2D relies on CSA1, its adjacent TIR-NB-LRR neighbor. Scientific Reports. doi:10.1038/srep08792. # 共同第一作者.
17. Xu S, Zhang Z, Jing B, Gannon P, Ding J, Xu F, Li X, Zhang Y. (2011) Transportin-SR is required for proper splicing of resistance genes and plant immunity. Plos Genetics. 7(6):e1002159.
18. Zhu Z, Xu F, Zhang Y, Cheng YT, Wiermer M, Li X, Zhang Y. (2010) Arabidopsis resistance protein SNC1 activates immune responses through association with a transcriptional corepressor. Proc Natl Acad Sci U S A. 107(31):13960-5.
19. Monaghan J, Xu F, Xu S, Zhang Y, Li X. (2010) Two putative RNA-binding proteins function with unequal genetic redundancy in the MOS4-associated complex. Plant Physiology. 154(4):1783-93.
20. Zhang Y, Xu S, Ding P, Wang D, Cheng YT, He J, Gao M, Xu F, Li Y, Zhu Z, Li X, Zhang Y. (2010) Control of salicylic acid synthesis and systemic acquired resistance by two members of a plant-specific family of transcription factors. Proc Natl Acad Sci U S A. 107(42):18220-5.
21. Xu F, Monaghan J, Chen S, Zhang Y, and Li X. (2009) Analysis of MOS4-Associated protein Complex (MAC) by immuno-affinity chromatography and quantitative mass spectrometry. Chapter 84 in Biology of Molecular Plant-Microbe Interactions, Volume 7
22. Monaghan J, Xu F, Gao M, Zhao Q, Palma K, Long C, Chen S, Zhang Y, Li X. (2009) Two Prp19-like U-box proteins in the MOS4-associated complex play redundant roles in plant innate immunity. Plos Pathogen. 5(7):e1000526.
23. Gao M, Wang X, Wang D, Xu F, Ding X, Zhang Z, Bi D, Cheng YT, Chen S, Li X, Zhang Y. (2009) Regulation of cell death and innate immunity by two receptor-like kinases in Arabidopsis. Cell Host & Microbe. 6(1):34-44.
24. Cheng YT#, Germain H#, Wiermer M#, Bi D#, Xu F, García AV, Wirthmueller L, Després C, Parker JE, Zhang Y, Li X. (2009) Nuclear Pore Complex Component MOS7/Nup88 Is Required for Innate Immunity and Nuclear Accumulation of Defense Regulators in Arabidopsis. Plant Cell. 21(8):2503-16. # 共同第一作者.
本实验室招收副研究员1名，博士后1名，博士1名，硕士3名，有意者请邮件咨询 (fxu@sdu.edu.cn)。
