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动物科学

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徐志刚

0531-88362647 xuzg(AT)sdu.edu.cn

教育背景

本科   1995.09 - 1998.07          烟台大学               生物化学

博士   1998.09 - 2004.01          复旦大学               遗传学


工作经历

2004.01–2004.12       中国国家人类基因组南方研究中心   科研人员

2005.01–2005.09       美国哈佛大学医学院               博士后

2005.10–2009.05       美国斯坦福大学医学院             博士后

2009.05–现在          山东大学生命科学学院             教授


科研方向

1. 听觉转导分子机制

2. 听纤毛发育及维持机制

3. 耳聋发生机制


论文

1. Liu C, Zhai X, Du H, Cao Y, Cao H, Wang Y, Yu X, Gao J, Xu Z*. Sorting nexin 9 (SNX9) is not essential for development and auditory function in mice. Oncotarget 2016 Sep 15. Advance publication.

2. Sun J*, Zhang D, Wang Y, Lin H, Yu X, Xu Z*. The role of G protein-coupled receptors in cochlear planar cell polarity. Int J Biochem Cell Biol 2016 Aug;77(Pt B):220-5.

3. Hu QX, Dong JH, Du HB, Zhang DL, Ren HZ, Ma ML, Cai Y, Zhao TC, Yin XL, Yu X, Xue T, Xu ZG*, Sun JP*. Constitutive Gαi Coupling Activity of VLGR1 and its Regulation by PDZD7. J Biol Chem 2014 Aug 29;289(35):24215-25.

4. Cao H, Yin X, Cao Y, Jin Y, Wang S, Kong Y, Chen Y, Gao J, Heller S, Xu Z*. FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro. PLoS ONE 2013; 8(2): e56516.

5. Sun J*, Li R, Ren H, Xu A, Yu X, Xu Z*. The very large G protein coupled receptor (Vlgr1) in hair cells. J Mol Neurosci 2013; 50:204–14.

6. Li H, Liu N, Wang S, Wang L, Zhao J, Su L, Zhang Y, Zhang S, Xu Z*, Zhao B*, Miao J*. Identification of a small molecule targeting annexin A7. BBA–Mol Cell Res 2013 Sep; 1832(9):2092-9.

7. Xu Z*, Oshima K, Heller S. PIST regulates the intracellular trafficking and plasma membrane expression of Cadherin 23. BMC Cell Biol 2010; 11:80.

8.Xu Z1, Ricci AJ, Heller S. Rethinking how hearing happens. Neuron 2009; 62(3):305-7.

9. Xu Z1, Peng AW, Oshima K, Heller S. MAGI-1, a candidate stereociliary scaffolding protein, associates with the tip-link component cadherin 23. J Neurosci 2008; 28(44):11269-76.

10. Xu ZG1, Du JJ, Zhang X, Cheng ZH, Ma ZZ, Xiao HS, Yu L, Wang ZQ, Li YY, Huo KK, Han ZG. A novel liver-specific zona pellucida domain containing protein that is expressed rarely in hepatocellular carcinoma. Hepatology 2003;38(3):735-44.


 

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